The Madison County Courier, Edwardsville, Illinois, Thursday, November 30, 1865

State Items
The small-pox has made its appearance in a very serious form among the citizens of Athens, in Menard county.

Submitted by:Brenda Hamilton Johnson

Urbana Daily Courier, July 29, 1903

Decrease in Smallpox Cases
During the past quarter smallpox has been reported from twenty-nine counties, at forty-six places in Illinois. A total of 120 cases has been recorded. This is a decrease of sixty per cent from the figures of the last preceding quarter. The greatest number of cases was reported from Williamson county, in the northern part of the state.

Smallpox has existed in the last three months at the following places: Bureau county, Spring Valley; Cass county, Beardstown; Champaign county, Champaign, Bondville and Scott township; Clark county, Martinsville; Clay county, Iola; Clinton county, Keysport; Coles county, Mattoon and Hutton township; Cook county, Chicago, Barrington and Glenwood; Cumberland county, Woodberry; Edgar county, Buck township; Effingham county, Altamont and Effingham; Fulton county, Piatt, London Mills and Dearfield township; Greene county, Greenfield and Carrollton; Grundy county, Eileen; Henry county, Osco and Annawan; Knox county, Galesberg and De Long; Lake county, Libertyville; La Salle county, Streator; Macoupin county, Girard; Madison county, Edwardsville Junction, Venice, Madison and Granite City; Massac county, Brockport; Menard county, Oakford township; Mercer county, Gilcrest; Pike county, Nebo and Pittsfield; Piatt county, Blue Ridge township; Sangamon county, Springfield and Curran township; Scott county, Bluffs; St. Clair county, Engelman township; Williams county, Herrin and Lake Creek.