Located in Lawrence and Beaver Counties, Enon Valley was Established 1839.

Enon Valley had a population of 387 with 149 housing units; a land area land area of 0.52 sq. miles; a water area of 0 sq. miles; and a population density of 746.50 people per sq. mile for Census 2000.

Enon Valley means "Valley Of Many Waters".

Enon Valley was the setting for some of the scenes in the 1996 Farrelly brothers movie Kingpin.